Mercury From Fish Can Affect Cognitive Function in Middle Aged Adults

In reviewing the latest information about mercury and cognition, I became aware of an article that appeared in the Integrative Medicine Journal a year ago.

To study looked at 384 men and women who were mostly corporate executives and who attended an all day company annual physical examination.

They measured the blood mercury levels in all the patients and then looked at the relationship between mercury and cognitive performance in the patients.

The finding was that participants with Mercury levels above 15 mcg/L,showed a 4 to 5% lower complex information processing (CIP)capability, which is commonly called executive function, when they did neurocognitive testing.


The interesting thing from the study was that in those patients with moderate fish consumption, 1 to 3 servings of fish per week, there was no measurable effect on their cognition. This was thought to be caused by the fact that the fish contain essential fatty acids which can improve cognitive function. Therefore the deleterious effects of the mercury were compensated for by the fatty acids in the fish.

The authors rightfully point out that “If cognitive neurotoxicity occurs in healthy, highly productive individuals with ample cognitive reserves, the effect is likely to be amplified in more vulnerable populations.”

They point out that cognitive decline and dementia are an increasing problem as our population is aging. Therefore as seafood consumption also rises in individuals who desire to eat a “heart healthy” diet, this relationship with increased mercury could have a large impact on quality of life, and healthcare costs into the distant future.

This is one of the first studies I’ve seen that actually looks at the effect of mercury on cognitive impairment in middle-aged people. The drawbacks of the study are that that they only looked at one blood specimen and compared it with the patient’s stated history of fish consumption. There is no measurement of mercury exposure over time in the patients.

An even bigger question is what were these patients “Total Body Load” of Mercury? This can only be determined by doing a challenged urine test, with a chelating agent.

What the authors do not point out is that after a person eats fish, the mercury is not eliminated from the body but rather goes into the organs, muscles and tissues of the body where it is stored for the rest of the person’s life! This burden of mercury produces a chronic stress on the neurological, immune, and endocrine system.

In my opinion, this total body burden plays a role in a wide range of diseases from multiple sclerosis to cancer.

The other thing the authors do not point out is that the amount of essential fatty acids contained in each fish serving could be replaced by one Eseential Fatty Acid capsule from the health food store.

My general recommendation to my patient population is still to avoid or minimize fish consumption and take one essential fatty acid pill per day.

Certainly women of childbearing age and women who are pregnant should avoid fish altogether in my opinion. Of course they must take one pill a day of DHA, an essential fatty acid, for their fetuses brain function, along with their traditional Prenatal Vitamin.

I predict that as the oceans increasingly concentrate more and more mercury, and the fish get higher and higher levels of mercury in them, that we will see much more about this in the years ahead.

Read the original article here

Read the whole article here

Read More on This Here:

Long term neurocognitive impact of low dose prenatal methylmercury exposure

Fish consumption, methylmercury and child neurodevelopment

Let me know what you think below!

Environmental Toxicity and Pregnancy-The Role of the Male

For many years, doctors, researchers and patients have all assumed that the primary responsibility for the state of the fetus was the mother, her health, her nutrients, her toxic exposures and her thoughts.

Recently, the new science called epigenetics has been burgeoning. I have mentioned epigenetics in my articles before. However, by way of summary, “epi” means “above” and therefore epigenetics means influences that are “above the gene”.

What does that really mean? It means that it is not just what genes we have, but what effects has the environment has had on these genes. Epigenetics determines how genes are turned on or off and this determines what proteins the genes make. These proteins then directly influence our health.

It is now coming to light that the health of the father’s sperm is of equal importance as the health of the mother during pregnancy in determining our children’s future health.

It turns out that the toxins that a man has been exposed to can end up affecting his sperm directly. What future parents should understand, and is now being proven, is that the health of their unborn children can be affected by what the man eats, the toxins he is exposed to, the traumas he has undergone, and his age at the time of conception. In other words, a man’s life experience leaves biological traces on his children. In addition his children can pass these biological markers on to their children.

This article shows that even fear can be transmitted through a man’s sperm.

All these influences on a man’s sperm occur through epigenetic mechanisms.  New research is showing this in the most astonishing way. For example, recent research has shown that Vinclozin, which is a fungicide that used to be sprayed all over our country, is able to block the production of testosterone. Male rats born to mothers who were given a significant dose of Vinclosin are highly likely to be born with defective testicles and reduced fertility. This is not a surprise and it’s what I’ve talked to you about in my previous articles. This is why mothers need to avoid these toxins during pregnancy and hopefully clean them out as much as possible before conception.

However the shocking result of this study is that the problems these baby rats were born with continue to reappear for up to four generations of male rats born after the mother’s exposure.

When a woman is born she has all the eggs she will ever have. However, by the time a man turns 40, his gonads cells will have divided 610 times to make his sperm. This gives an increasing chance for epigenetic changes to occur to his DNA that will subsequently affect his child and his future generations.

Dr. Michael Skinner is one of the foremost researchers and a founder of this science of epigenetics. Dr. Skinner was the first to do the study mentioned above on Vinclosin.

After his findings with Vinclosin, he subsequently tested additional substances that lead to diseases in the rat’s prostate, kidney, ovaries and immune system. Repeatedly these diseases also showed up in the fourth and fifth generation offspring of mothers who had been exposed to the chemical.

To quote Dr. Skinner: “In essence, what your great-grandmother was exposed to causes disease in you and your children.”

What Dr. Skinner also found was that these changes did not occur in the actual genes themselves but rather by the patterns of simple molecules called methyl groups that attach to the cells that eventually become eggs or sperm.

Methyl Group on DNA

These methyl groups are just a carbon atom with three hydrogen atoms attached. Methyl groups stick like “burrs stuck to a knit sweater

and interfere with the functioning of the DNA. Dr. Skinner found that these “burrs” stayed on the DNA for generations.

Dr. Skinner thereby coined a new field of medicine called “Transgenerational Epigenetics”. This is the study of inherited changes that cannot be explained by traditional genetics.

Dr. Skinner has gone on to do more research, as noted above, with additional chemicals including insect spray, jet fuel and BPA. He has found that each exposure leaves a distinct pattern of methyl group arrangements and that these persisted into the great-grandchildren of exposed rats.

This is like your grandmother’s environmental exposure leaving a fingerprint on your genes that scientists can now actually trace.

A practical example of this is that Dr. Skinner has determined that exposure of rats to the chemical DDT can lead to obesity in the subsequent generations. Since every patient I test for DDT does have it in their body, could this be a contributor to our current epidemic of obesity?

In terms of preconception pregnancy planning, my big question is, will an intensive detoxification and chelation program be able to reverse the epigenetic changes that have occurred to a man’s sperm? And, is it thereby worthwhile for a man to do a detox before his wife conceives?

This is all cutting-edge research, and some of it is still thought to be controversial by very orthodox physicians. But it makes total sense to me and to my colleagues in integrative medicine that transgenerational epigenetics is playing a role in our health and in the health of our great-grandchildren.

Leave your comments below or find me on Twitter or Facebook and leave me a comment there!

Also remember to visit my Healthy Living Shop where you can get physician quality supplements for you health!

More Reading

Memories pas between generations

The toxins that affected your great-grandparents could be inyour genes

Dioxin directly affects the sperm

Why fathers really matter

Epigenetics and environmental chemicals

Paternal Stress Exposure alters offspring’s stress axis

Epigenetic inheritance through sperm

How genes turn on and off, methyl groups, and epigenetics

Vitamin D Deficiency Again Associated with Increased Risk of Breast Cancer Recurrence and Death

Another major article showing the relationship between vitamin D level and breast cancer prognosis has just been published. This was a study which is called a “Meta analysis”. This is the type of study that reviews several other articles and then summarizes and integrates their findings.

In this study the researchers looked for studies that obtained vitamin D levels at the time of non-–metastatic breast cancer diagnosis and then measured the clinical outcomes of recurrence, distant recurrence, death and breast cancer specific death.

Researchers found eight studies that met their criteria for inclusion, and that included 5691 patients.

The findings of this study were:

1. All six of the studies found that vitamin D deficiency is associated with an increased risk of breast cancer recurrence.

2. When the studies were brought together there was a 2.13 times increased associated risk of having a breast cancer recurrence if the patient was vitamin D deficient compared to having enough vitamin D.

3. All six of the studies found that vitamin D deficiency was associated with an increased risk of death.

4. When the studies were all brought together there was a 1.76 times increased associated risk of death if the patient was vitamin D deficient compared to those who were sufficient.

The researchers concluded “We have identified statistically significant associations of low levels of vitamin D, measured around the time of breast cancer diagnosis, with an increased risk of recurrence and death in early-stage breast cancer patients.”

Researchers pointed out, as I’ve pointed out in my book and in my lectures, that these studies are still “observational”, and therefore cannot come to a 100% conclusion that there is a *causal connection* between vitamin D deficiency and a risk of recurrence and death from breast cancer.

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The study that needs to be done to prove the direct relationship between vitamin D and breast cancer would be a double-blind crossover placebo study. In this study one group of women with breast cancer would get the vitamin D and the other group would not. They would then be followed over 5 to 10 years to see which ones died.

The obvious problem with such a study in this day and age with the Internet, is that women with breast cancer often begin taking vitamin D themselves even though their oncologists are not prescribing it. This is a good thing but therefore would make this type of study very difficult to run.

My position remains the same as it has been since I wrote my book. Since there is no harm in normalizing one’s vitamin D blood level, everybody including women who have been diagnosed with breast cancer, should do that.

If the double-blind placebo-controlled trials which will come out in the next 10 years do prove there was be a benefit,(they will) then we all got the benefit early and this may prevent a disease in us. If it shows no benefit, there has been no harm in normalizing our vitamin D level.

At this time of year, Thanksgiving and Christmas, when most of our country is in what we call the “Vitamin D Winter”, have you checked your blood level of vitamin D recently? Are you taking vitamin D? Are you giving it to your children?

Here is a nice interview with Dr. David Feldman, Professor Emeritus, Medicine Endocrinology, Gerontology & Metabolism Stanford University School of Medicine about Vitamin D and its relationship with breast cancer.

This was an interview conducted by Carole Baggerly during the Linus Pauling Institute Conference 2013.

Please let me know your thoughts in the comments below.

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Fish Consumption Associated with Brain Shrinkage in Newborns

Physicians have known for many years that mercury in the human body is associated with neurological damage. Fish consumption is the main source of mercury in the human body.

Now a new video from my colleague Michael Greger, M.D.(see below) brings together several journal articles which specifically show how methylmercury in fish is damaging the human brain.

We have known for some time that there is a dose‚ a response relationship of prenatal mercury exposure and IQ. Dr. Greger’s video pointed out to me an article that appeared in the medical literature several years ago on the relation of mercury and newborn’s brains. This article specifically shows that there is a direct relationship between prenatal exposure to a low level of mercury in the mother, and the size of a newborn’s cerebellum.

Specifically in this article it was shown that “prenatal exposure to, what we consider to be, low levels of methylmercury does influence fetal brain development detected as decreased size of the newborn cerebellum.” The decreased size of the newborn cerebellum was up to 14% smaller in length.

What is the cerebellum and what does it do? First of all the cerebellum which is known as the “little brain” is the second largest part of the brain and is located near the base of the brain. Although the cerebellum accounts for only about 10% of the brain’s volume, it contains over 50% of the total number of neurons in the brain.


What is so important about this ? Traditionally the cerebellum has been considered a purely motor control device. However this is now appearing to not be true. Specifically as recently reported in Brain:The Journal of Neurology, researchers have found connections between the cerebellum and the hypothalamus in the brain. These pathways connect with neural circuits that govern intellect, emotion and autonomic function as well as sensorimotor control.

There is a condition called Cerebellar Cognitive and Affective Syndrome (CCAS). This condition occurs in adults and children with stroke or tumor involving the cerebellum. It is also seen in children born very preterm who have a small cerebellum.

The neurobehavioral deficits that occur in this condition can occur in the absence of a motor condition. They are characterized by “impairments in executive function, which includes planning, set shifting, verbal fluency, abstract reasoning, and working memory.” In addition, “impairment in spatial cognition and linguistic processing as well as a dysregulation of their affect” is seen in patients with this condition.

These latter symptoms sound very much like the symptoms that children with Autism Spectrum Disorder, and Attention Deficit Disorder (ADHD)have. We now have an epidemic in our country of neurodevelopmental disorders with an estimated one in five children growing up to have such a disorder. Could mercury be part of the cause?

Watch the video now!

So, given this new information on mercury and the fetus, my first question is how much fish, which is loaded with mercury, is good for a woman while she’s pregnant? The second question is how much mercury has been accumulated by the woman before she conceives which then comes out during pregnancy and affects the fetus and its brain?

The other interesting aspect of this research was the amount of mercury the researchers considered “high” in the mother. The so-called “high levels”, were approximately 1/3 of the level of mercury a woman would get if she ate one can of tuna per week. I find young women in my practice eating tuna sushi several times per week.

In the studies I quoted above, researchers used hair mercury, which is one indication of the body load of mercury. However we now know that not all women excrete mercury into their hair even if they have it in their body.

We realize that the best test for body burden of mercury, is a challenged urine, where a woman takes a medication that is known to be able to pull mercury out of her tissues and put it in the urine where it can be measured.

This is the exact protocol that environmental doctors have been using for so many years. And this in part is why I encourage women in my Preconception Pregnancy Planning Program to get as much mercury as possible out of their body before they conceive.

I encourage you to share this information with your friends and family who are of childbearing age. Encourage them to get off fish before and during pregnancy, and encourage them to find a doctor who can measure their body load of mercury and help clean it out, before they conceive. Nobody wants a child with a small cerebellum, now that we are realizing the importance of this major part of our brain.

Please post your comments below!

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What is the Biggest Fear of Americans?

chronic illness
Getting diagnosed with a chronic illness like diabetes trumped other common fears of Americans such as the uncertain state of the economy, debt, job loss and leaving a loved one, according to a recent survey.

The puzzling part is that despite the survey results, a very small number of people have made any changes to their diet or lifestyle to reduce their risk of diabetes and other chronic illnesses — even though most people know lifestyle to be the cause of many illnesses.

Today this has become the direct equivalent to such time bombs as continuing to smoke while knowing it causes lung cancer and dramatically reduces life expectancy.

Diabetes afflicts one out of every four Americans and most of those with the disease don’t even realize they have it. Additionally, there are 57 million Americans with pre-diabetes. This is where the blood glucose levels are higher than normal, but not high enough to be officially diagnosed as diabetes.

“We know Americans view activities like bungee jumping as especially risky and so they avoid them, “ said Richard M. Bergenstal, MD, President-Elect, Medicine & Science, American Diabetes Association. “However these same people are gambling daily by ignoring risk factors for a life-altering disease like diabetes and doing nothing about it.”

Click here to read more.

How to Prepare for Thanksgiving Without as Much Stress

While most people visualize their Thanksgiving Day as a warm and loving time surrounded by family, cozy aromas of turkey and stuffing cooking in the oven and feelings of gratitude, it can also induce stress brought on by high expectations, hectic preparation for the big day, family spats and nagging worries of overeating. It’s things like this that build up and many times take the joy out of what could be a beautiful Thanksgiving holiday.

With some careful preparation and a bit of organization, Thanksgiving day can turn into the warm, memorable holiday you’ve imagined.

The key is to be prepared in advance before the holiday to create your ideal Thanksgiving, one without stress and chaos.

If you are hosting Thanksgiving dinner there are 10 things on your checklist to make it as stress-free and enjoyable as possible.

Click here to view the checklist.

Why are Babies Being Born Toxic… and What Does This Mean for YOU and Your Family?

pregnancyBabies, who represent what is most innocent and pure about humanity, are being exposed to high levels of chemicals while still in the womb. Sadly, this chemical exposure leads to babies being born toxic with greatly heightened potential to develop chronic diseases much earlier in life.

The findings were revealed by an Environmental Working Group (EWG) study of the umbilical cord blood of 10 newborn babies in the United States. The umbilical cord is a good measure of contaminants because it pulses the equivalent of at least 300 quarts of blood each day back and forth between the placenta and the child.

While it was once thought that the placenta acted as a shield, protecting the baby from most chemicals and environmental pollutants, EWG found this is not the case. Researchers wrote in Body Burden – The Pollution in Newborns executive summary:

“Not long ago scientists thought that the placenta shielded cord blood — and the developing baby — from most chemicals and pollutants in the environment.

Click here to read more.

United Steel Workers Issue Breast Cancer Hazard Alert!

For many years, environmental doctors including myself have been asking our government and the women of the world, to pay attention to Endocrine Disrupting Chemicals (EDC’s),and the role they are playing in the current epidemic of breast cancer.

In my own practice, my to help efforts have been to help my patients to understand that even the cosmetics and personal care products that they are using on their skin every day can disrupt their hormonal system,and thereby contribute to their development of breast cancer.

In addition, chemicals in the air we breathe similarly can disrupt our endocrine system. Specifically these chemicals are known as xeno-estrogens. This means “foreign” estrogens.

I’m delighted to see that organizations as prominent as breastcancer.org, are mounting campaigns to teach women how to avoid these kinds of chemicals.

Many new cosmetic and personal care products companies are opening and leaving these harmful chemicals out of their new products.

My colleagues at the Environmental Working Group have led the way with their Safe Cosmetics Database. This database has been on their site for many years and they have evaluated over 79,000 personal care products and rank them according to their safety.

This even counts men’s personal care products such as shaving cream, which can disrupt their endocrine system, contributing to prostate cancer.

Many industries as well as high-ranking officials in our national government, have been in denial about these effects for a very long time.

Now with the publication of a new article showing a direct link between breast cancer in certain occupations, I am delighted to see the United Steel Workers step out of the shadows and call for action to be taken to protect their female workers.

That is because of this recently [published article in Environmental Health. You might say that they have been forced to bring this to light because this study has shown that young women in the automotive plastics industry are up to five times more likely to have breast cancer than their peers working in other industries.

I am delighted to see that the United Steel Workers in their announcement are calling for their “Collective voice to win health and safety improvements in our workplaces, such as substituting less hazardous chemicals… to prevent worker exposures to harmful chemicals.”.

In addition, more and more organizations are forming to refocus our approach to breast cancer on prevention rather than only treatment. the Alliance for Cancer Prevention is leading the way in Europe..

Physicians, including myself, are now able to measure at least some of the endocrine disrupting chemicals in our patients. I do this routinely on patients who come to me after a diagnosis of breast cancer, in an effort to help them prevent a recurrence. However this can be done in interested women in an effort to help prevent a primary breast cancer.

Please help spread the word to your girlfriends and your children to avoid Endocrine Disrupting Chemicals, of which phthalates are the most common type, as much as you possibly can.

Insist on buying phthalate free personal care products and make up. If we all talk loud enough the big-name cosmetics companies will be forced to get these chemicals out of their products.

For more information on phthalates click here.

Click Here to see a fact sheet showing which factors increase and decrease breast cancer risk

For more information on EDC’s click here.

Here is a another article on chemicals in the workplace and women’s health

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11 Rare Diseases You’ve Never Heard Of

rare diseaseIn the United States, a disease is generally considered rare if it occurs in less than 200,000 people. Those who suffer from these so-called “orphan” diseases often go undiagnosed for years, and then are left with little to go on in terms of treatment, known causes and cures.

In honor of Rare Disease Day, which is coordinated by the National Organization for Rare Disorders and is coming up in February, we’re highlighting 10 rare diseases that many people have never heard of, in order to broaden horizons and promote awareness of these conditions.

This is just a small sampling of the nearly 7,000 rare diseases recognized by the National Institutes of Health Office of Rare Diseases Research. To learn more about a particular rare disease, you can visit their site directly.

Click here to find out about some rare diseases. 

Are you Toxic Rich, Health Poor?

 Even in some of the richest countries in the world, environmental toxins could be making you “health poor.” In fact, even with the best diet, regular exercise and an optimistic outlook, your health can be impacted by the air you breathe, the water you drink, the food you eat, and even the soil in which your food is grown.

Are These Eight Top Environmental Toxins Making You “Health Poor”?

More than 80,000 industrial chemicals have found their way into the U.S. environment over the last 50 years.

Contrary to popular belief, most of these chemicals have never been safety tested for use with humans, animals or the environment, and many environmental chemicals cannot be seen, smelled or tasted — but that doesn’t mean they are inert.

Click here to read more.