High Prevalence of Vitamin D Deficiency in Pre-Menopausal Women with Breast Cancer

pre menopausal breast ca In my book on vitamin D, I discuss the importance of vitamin D as observed from retrospective and epidemiologic studies in helping to prevent breast cancer and the recurrence of breast cancer.

I also mention in my book that as of the date of publication and even to this date I have not seen one breast cancer patient come to my office for immune support as an adjunct to their traditional breast cancer therapy who have had a vitamin D blood level measured by their oncologists.

Now a recently published study by KD Crew and colleagues looked at the frequency of vitamin D deficiency in premenopausal women who were diagnosed with breast cancer and undergoing adjuvant chemotherapy. Adjuvant therapy means therapy that is in addition to the primary chemotherapy that a woman would receive after a diagnosis of breast cancer.
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Canned Foods and BPA

BPA and health and endocrine disruptorsBisphenol A (BPA) is a common environmental toxin which I have mentioned before, that often appears in plastic bottles. BPA can disrupt the way hormones carry signals in our body and for that reason it is known as a "endocrine disruptor." Because we only need a few hormone molecules to send signals in our bodies, endocrine disruptors are able to interrupt healthy signals at very low concentrations — in fact even a few parts per trillion of BPA has been shown to disrupt normal endocrine signaling that can lead to health problems.

The following are health impacts that have been linked to low level exposure to BPA in either animals or humans:
-Obesity
-Low sperm count
-Damage to developing eggs
-Miscarriage
-Placental cell death
-Infertility
-Heart disease
-Diabetes
-Changes in brain development
-Predisposition to breast and prostate cancer.

A new report called No Silver Lining — An Investigation into Bisphenol A in Canned foods has recently been released by the National Workgroup for Safe Markets which is a coalition of US public health and environmental health focused NGOs.

This report reviews the data on BPA. It points out that Canada,Denmark and five US states have already restricted the use of BPA in certain children's products like baby bottles and infant formula can linings.

In this report that Workgroup was looking at the amount of BPA that could be consumed from eating canned food and drinks that are commonly available in the United States and Canada. For this study they collected and tested the food and beverage contents of 50 cans that were collected from 19 United States and Ontario, Canada.
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Reducing Environmental Cancer Risk-The President’s Report

presidents cancer report toxins A new report has come out from the President's Cancer Panel which was written by .LaSalle Leffell, Jr.,M.D.,F.A.C.S, and Margaret Kripke Ph.D. The title of the report is Reducing Environmental Cancer Risk — What We Can Do Now.

This report points out that in 2009 approximately 1.5 million American men women and children were diagnosed with cancer and 562,000 died from the disease. Approximately 41% of Americans will be diagnosed with cancer at some point in their lives and approximately 21% will die from cancer.

This report was brought about because of the growing body of evidence that links environmental exposures to cancer. The report points out that the" public is becoming increasingly aware of the unacceptable burden of cancer resulting from environmental and occupational exposures they could have been prevented through appropriate national action."

One of the findings of the panel that particularly concerned them was the finding that the true burden of environmentally induced cancer has been "grossly underestimated". They point out that nearly 80,000 chemicals are on the market in United States that are being used by millions of Americans in their daily lives. These chemicals have either been understudied or unregulated. They point out that one such chemical, BPA, is still found in many consumer products and remains unregulated in our country.
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“Solving the Problem of Childhood Obesity Within A Generation”

The White House task force on childhood obesity has just released its report to the President entitled "Solving the Problem of Childhood Obesity Within a Generation." This fits in well with Michelle's Obama's cover article in Newsweek recently.

This 120 page report looks at the current epidemic of childhood obesity. Some of the statistics are overwhelming. Currently one in every three child ages to 19 is overweight or obese. Obesity is estimated to cost 112,000 deaths per year in the United States. One third of all children born in the year 2000 are expected to develop diabetes in their lifetime. In addition, a recent article in the New England Journal of Medicine has pointed out that for the first time the current generation of children may be on a course of having a shorter life span than their parents.

There has been a consistent increase in the growth of childhood obesity from 1971 until about the year 2000, at which time childhood obesity levels off.

This very thorough report looks at many aspects of the cause of this epidemic and is full of amazing information. A few of these are
1)    Obese adults in current estimated $1429 more in medical expenses than their normal weight years.
2)    Medical spending on adults that was attributed just to obesity was over $40 billion in 1998. But in 2008 this had increased to an estimated $147 billion.
3)    During childhood excess weight costs an estimated $3 billion per year in direct medical costs.
4)    At least $1.6 billion is spent annually on food advertising directed to children and adolescents.
5)    13% of the daily caloric intake for 12 to 19-year-olds now comes from sugar- sweetened beverages.
6)    On average, children consumed only 64% of the recommended level of fruit and 46% of the recommended level of vegetables in 2003 to 2004.
7)    A mother's preconception weight and weight gain during pregnancy are two of the most important prenatal determinants of childhood obesity. Another way to say this is overweight mothers give birth to overweight children.
8)    Maternal smoking girly pregnancy is associated with a 500% greater risk of obesity at age 5.
9)    Research shows that it is possible that exposure to endocrine disrupting chemicals during pregnancy play a role in the development of childhood obesity. Scientists have coined the term "obesogins" for chemicals that they believe may promote weight gain and obesity.
10)    The Federal Trade Commission (FTC) estimated that in 2006 the food, beverage, and quick serve restaurant companies spent more than $1.6 billion to promote their products to young people.

The statistics in this article go on and on but it is clear that our entire country must change its direction in eating, exercise and focused in order for us to be first the obesity epidemic that we are living with.

The report focuses on five basic things that we can all do together to help this epidemic:
1) Create a healthy start on life for our children, from pregnancy through early childhood;
2) Empower parents and caregivers to make healthy choices for their families;
3) Serve healthier foods in schools;
4) Ensure access to healthy, affordable food;
5) Increase opportunities for physical activity.

I encourage you to read the whole article which can be gotten at this website.
Let me know what you think. Do you talk to your overweight friends about diet and exercise? What do you think can be done to improve this obesity epidemic?

The Government's Food Pyramid

“Confronting Cancer as a Chronic Disease”- The IFM Convention


I am just recently back from the Institute for Functional Medicine (IFM) convention in Carlsbad, California. The subject of this year's symposium was "Confronting Cancer as a Chronic Disease: Primary Care Taking a 360-degree View."

In all, 21 countries were represented and attendance was sold out at 600 people.

I have been a member of the Institute for Functional Medicine since its inception. It was created by my longtime friend and colleague Dr. Jeffrey Bland.

The 4 day conference had a full schedule with lectures starting at 7 AM and closing around 6:30 PM every night.

Even though I have attended so many other IFM conventions, this is probably the best one I have ever attended. All aspects of integrative oncology were discussed. Lectures on the role of antioxidants in cancer prevention and treatment were part of the conference. Other topics were nutritional and botanical support during cancer therapy, individualizing nutrition protocols to complement Cancer care, and using biomarkers for primary prevention in secondary recurrence of common cancers.

The conference was organized by my friends Mary Hardy, M.D. and Dwight McKee, M.D, Ph.D.  Dwight and I attended medical school together and were friends throughout school.

Mary and Dr Soram

                Dr Soram with Mary Hardy, M.D.

 

            Dr Soram with Dwight McKee, M.D. Ph.D

Two of the most prominent speakers were Dr. Dean Ornish, and Dr Keith Block. Dr Ornish gave a lecture entitled "The Power of Sustainable Changes in Diet and Lifestyle". Dr. Ornish has carried over his amazing findings on diet and lifestyle for the benefit of heart disease and is now using it to benefit cancer patients. You can pick up his new book by clicking HERE.

Dr. Ornish was also the recipient of the Linus Pauling Person of the Year award, given for his work showing the benefit of diet and lifestyle for chronic disease. I was delighted to learn during his lecture that he was a student of Swami Muktananda, who was very good friends with my teacher Yogi Bhajan, and I was able to share a few words with Dr. Ornish about our teachers, and have a photograph taken with him and at the end of his speech.

 

            Dr Soram with Dean Ornish, M.D.

 

Dr. Keith Block gave an information packed lecture entitled "Long-Term Biologic Strategies for Ssecondary Prevention of Cancer". Dr Block has written a great book explaining his approach to integrative oncology. You can pick it up HERE.

Some of the lectures were very medically detailed. However, many were understandable by lay people and I wish some of my cancer patients had been able to attend some of these wonderful lectures and learn. In any case I am bringing back to my practice all the exciting new information about using integrative medicine for cancer patients. For those of you who would like to get a sample of these lectures, I am delighted to say that Jeffrey Bland's opening talk entitled "Looking Anew at Cancer" is available online for free by clicking this link.

I have already shared some of the new information from this convention in my blog and I look forward to sharing much more over the weeks ahead with all my readers.

 

Vitamin K and A New Theory of Chronic Degenerative Disease

K and degeneration and triage Dr. Bruce Ames has been one of the brightest minds over the last decades in the world of biochemical nutrition. He is now in his 80s and for the last years, he has been writing about his theory of the development of chronic degenerative disease, which he calls “Triage Theory”.

In a new article by Dr Ames and his colleague, Joyce McCann, the authors discuss this new theory. This theory is based on the question “Is micronutrient inadequacy linked to diseases of aging”? Micronutrients include everything from zinc and selenium to vitamin D and vitamin K, all of  which we get in small quantities in our diet.

In this article, they specifically look at vitamin K. What they propose is that when  our body has a limited amount of a given nutrient e.g. vitamin K, it shunts the nutrient to the biochemical processes that are most needed for immediate survival. The theory is that when there is not enough of the nutrient over many years, other biochemical processes that are important, but which do not lead to an acute problem, do not receive a sufficient amount of the nutrient over a long period of time. This insufficiency does not produce immediate problems. But what this theory says is that this long term deficiency of the nutrient neededfor these other essential biochemical processes leads to chronic degenerative diseases, rather than an acute medical problem.

In this article they specifically look at vitamin K. Vitamin K’s immediate use is to allow our blood to coagulate. So if you only have a small amount of vitamin K it will be used primarily to allow your blood to coagulate so you do not bleed to death. However what they point out in this study, is that long-term relative deficiency of vitamin K is linked to several age associated conditions. These include bone fragility after menopause, and arterial calcification which is linked to cardiovascular disease. Also in animal models an increased incidence in  cancer has been observed in long term vitamin K deficiency.

This theory is completely compatible with Dr. Robert Heaney’s concept of “long latency deficiency diseases” which is discussed extensively in my book on vitamin D. In the case of vitamin D, an immediate deficiency will lead to rickets. However from all the research, it appears that a long term low-level deficiency of vitamin D leads to increased risk for cancer, heart disease, diabetes high blood pressure, osteoporosis etc.
I really like this theory! Whether we call it “triage theory” or “long latency deficiency disease theory,” this concept makes enormous sense to me. The profound changes I have seen in my own practice of medicine as well as in my own health, from optimizing vitamin D levels, has shown me that vitamin D in higher levels bestows many additional benefits besides the prevention of rickets. It makes total sense to me that  our current epidemic of chronic diseases and fast food, can be linked to a relative insufficiency of many of the micronutrients that we all will get if we eat a healthy diet.

I have attempted to explain these complex concepts in a way that is understandable for you my readers. Please let me know if you have questions? Please let me know what your thoughts are on these concepts? I look forward to hearing back from you.

REFERENCE

Summer is Here! Choose Your Sunblock Carefully ! Here is How!

sun block skin cancer safe I am honored to be a friend of Ken Cook who is the president of the Environmental Working Group (EWG). I have been an admirer of their work for many years and I am delighted to see they are coming into the mainstream. This was the organization that conducted the seminal study about five years ago that showed that children born in America were receiving up to 287 chemicals in the placenta throughout pregnancy.

Now, The Environmental Working Group has come out with its new Sunscreen Guide. Of note, they evaluated over 500 sunscreens and could only recommend 39 of these (8% of the total).

There were several reasons they recommended so few of the hundreds of sunscreens that are available:

1) They found that there were a large number of exaggerated SPF claims over 50. High SPF products often give consumers a sense of safety in prolonged sun exposure. These high SPF products also generally do not block UVA radiation. UVA radiation is associated with skin cancer and particularly the very dangerous type called melanoma.

2) EWG also evaluated hazardous ingredients very closely. Specifically they looked at new data from the government that links vitamin A in sunscreens to the accelerated development of skin tumors and lesions. The particular type of vitamin A in sunscreens that is being investigated is called retinyl palmitate.

3) EWG also removed from its list, products containing oxybenzone because it is a known hormone disrupting compound and is found in about 60% of the sunscreens they analyzed. This chemical enters the bloodstream and has been found in the bodies of about 97% of Americans tested.

EWG GREEN RATINGS

 The 39 beach and sports products that earned EWG's "Green" rating for safety and efficacy all contained the minerals zinc or titanium. You can jump right to them by clicking here

EWG also goes on to expose 8 surprising truths about sunscreens:
1)    There is no consensus on whether sunscreens prevent cancer.
2)    There's some evidence that sunscreens might increase the risk of the deadliest form of skin cancer for some people. As I noted above this is because they do not protect from UVA rays.
3)    There are more high SPF products than ever before, but no proof that they are better.
4)    Too little sun might be harmful, reducing the body's vitamin D levels. My readers certainly know about this!
5)    This common sunscreen ingredient vitamin A may speed the development of cancer
6)    There are skin damaging byproducts of sunscreen, including the creation of free radicals
7)    Pick your sunscreen: nanomaterials or potential hormone disruptors! EWG recommends mineral sunscreens have the best safety profile amongst today's choices.
8)    Europe's better sunscreens. This is because in Europe, sunscreen makers can choose from among 27 chemicals for their formulations versus only 17 in the US.
9)    This is the 33rd summer in a row without final US sunscreen safety regulations.

I am very pleased that the EWG has released these recommendations, and I encourage you to follow them to provide for the safety of your family and yourself. Click here to go right to the brands they recommend.

Remember a few minutes in the sun before your sunblock (depending on your skin type) can give you vitamin D all summer.

 

Post Menopausal Breast Cancer Treatment and Vitamin D

Breast cancer and Vitamin D letrozole Postmenopausal women who are diagnosed with what is called "estrogen positive" breast cancer are usually given a drug called an Aromatase Inhibitor to take for five years.  Aromatase is the name of an enzyme in the body that converts testosterone to estrogen. In women whose breast cancer had estrogen receptors, doctors try reduce the amount of any estrogen in their bodies. Aromatase Inhibitor drugs block the making of estrogen. Studies have shown that this will reduce the likelihood of a woman's breast cancer coming back. Who would not want that benefit?

The problem with this family of drugs however is that it has side effects. Two of the most common side effects are joint pains almost to the point of being disabled and fatigue. Up to 50% of women treated with these drugs have new or increased joint pain or stiffness. 30% of women taking these drugs complained of fatigue. The degree of joint pain is so significant that one study showed that 22% of women discontinued the drugs because of this side effect.
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Blog Post Comments

Blog posts moved here for you to foloow My new web address for my blog was moved here some time ago. However some of my friends have been posting to the old blog page as they had my blog in their cache.

All of the comments from the old blog are now moved to THIS blog and I am putting all the most recent comments as comments to THIS blog post so they will be easy for you to find.

I look forward to staying in touch with my readers!     Dr Soram

Food Allergies and Irritable Bowel Syndrome (IBS)

Irritable Bowibs integrative medicine food allergies igg el Syndrome (IBS) is one of the most frequent diagnoses in any primary care practice in our country and probably around the world. Irritable Bowel Syndrome is a name that has been put on the condition in which the patient has intestinal gas, bloating, burping, diarrhea and/or alternating constipation, with a general unpleasant feeling in the gastrointestinal tract.

In conventional medicine when a patient has these symptoms they may get a stool test, colonoscopy and an upper G.I. endoscopy. If all these tests are normal the patient is then told that he or she has "Irritable Bowel Syndrome", and "nothing to worry about". However the symptoms can be quite bothersome and will often lead the patient to seek out the care of an integrative physician.

Integrative doctors in general and my practice in particular know that this diagnosis is a kind of "wastebasket" diagnosis that people are lumped into. With thorough investigation from an integrative medicine point of view many underlying causes can be found that are completely treatable and symptoms disappear.

One of the most common causes of these symptoms is food allergies. Conventional doctors only will call a food an allergen if when the patient eats that food, they break out in hives and a rash all over their body and require emergency care. Integrative doctors know that more subtle allergic reactions can cause the symptoms of IBS.

An article by PJ Whorwell and colleagues, several years ago looked at an additional way to find food allergies. Specifically this blood test looks for "IgG: antibodies in the blood. I've been doing blood tests for this type of food allergy for several years and have found it to be extremely valuable in helping people with the symptoms of IBS.

This study took a group of patients with Irritable Bowel Syndrome and did the IgG antibody blood tests on them. They followed the patients over 12 weeks. For those patients who were fully compliant with the diet recommended by the blood tests, there was a 26% reduction in symptoms. In addition other nonspecific symptoms including quality of life and anxiety/depression also improved in these patients.

I was delighted to recently find this study which confirms what integrative doctors have been doing for some time. In my practice, this is just one of several tests that I do to help patients resolve their IBS. And I have seen remarkable results with this.

If you have symptoms of IBS, please ask your doctor to do the IgG antibody blood test to see if you have food allergies. Then follow the diet prescribed by the blood tests and see if your symptoms go away.

Let me know if you have found food allergies to be relative to your symptoms and whether a specific diet has been helpful to you in minimizing intestinal symptoms? Questions? Let me know here

I look forward to hearing from you.

Dr. Soram

Reference